Introduction: Political regimes differ in their ways of dealing with minority issues, and specifically on the measures and recommendations issued with the Declaration. Twenty years has passed since the Declaration was issued and many states in my region, the Middle East, don’t even recognize the existence of ethnic, linguistic and religious minorities. In a region which is very rich with its multiplicity of minorities, very little progress has been made so far in implementation of the declaration on the official and popular fronts. I will briefly summarize in my short comments the challenges and difficulties facing the implementation of the declaration and specifically in the Middle East region. I will divide those challenges into four categories, for the reason of simplicity to come up with proper recommendations. Political Challenges: 1- Most of the regimes in the region run very closed political systems that monopolizes power in a way that does not spare any space for other groups especially minorities to participate in the government. In most cases minorities are not becoming integral elements in governing the states affairs. 2- Governments also don’t recognize the existence of minorities, let alone their rights. This is reflected in all policies that don’t even consider the presence of minorities and their interests. No accurate information about their number and status is available. 3- The absence of institutionalized state agencies that deal with minorities' issues leads to weak implementation of the declaration and unaccountable authorities.