Political Declaration on HIV and AIDS: On the Fast Track to Accelerating the Fight against HIV and to Ending the AIDS Epidemic by 2030 A/RES/70/266 44. Express grave concern that, despite a general decline in discriminatory attitudes and policies towards people living with, presumed to be living with, at risk of and affected by HIV, including those co-infected by tuberculosis, particularly in countries with a high tuberculosis/HIV burden, discrimination continues to be reported, and that restrictive legal and policy frameworks, including those related to HIV transmission, continue to discourage and prevent people from accessing prevention, treatment, care and support services; 45. Note with grave concern that, despite the recognition of the need to promote, protect and fulfil the human rights and fundamental freedoms of persons with disabilities, including as set forth in the Convention on the Rights of Persons with Disabilities, and despite the increased vulnerability to HIV infection faced by women and girls living with disabilities resulting from, inter alia, legal and economic inequalities, sexual and gender-based violence, discrimination and violations of their human rights, the formulation of the global AIDS response remains inadequately targeted and accessible to persons with disabilities; 46. Remain concerned that discriminatory laws and policies that restrict movement of people living with HIV may result in substantial harm and denial of HIV services, while acknowledging the steps taken by some countries in repealing entry, stay and residence restrictions based on HIV status and that many corporate leaders promoted the business case for non-discrimination; 47. Note with grave concern that the holistic needs and human rights of people living with, at risk of and affected by HIV, and of young people, remain insufficiently addressed because of inadequate integration of health services, including sexual and reproductive health-care and HIV services, including for people who have experienced sexual or gender-based violence, including postexposure prophylaxis, legal services and social protection; 48. Welcome the important progress achieved in research for new biomedical tools for prevention, notably regarding treatment as prevention, pre-exposure prophylaxis and antiretroviral-based microbicides and voluntary medical male circumcision, but also recognize that research and development must be accelerated, including for long-acting formulations of pre-exposure prophylaxis, preventive and therapeutic HIV vaccines and curative interventions; 49. Recognize that each country faces specific challenges to achieving sustainable development, and we underscore the special challenges facing the most vulnerable countries and, in particular, African countries, the least developed countries, landlocked developing countries and small island developing States, as well as the specific challenges facing the middle-income countries, and note that countries in situations of conflict also need special attention; 50. Acknowledge the significant mobilization of resources globally that reached an estimated 19.2 billion United States dollars for HIV programmes in low- and middle-income countries in 2014, 26 and acknowledge the important role played by complementary innovative sources of financing; 51. Welcome the near tripling of domestic HIV investment between 2006 and 2014, with domestic sources accounting for 57 per cent of all investments in 2014, and note the role that the African Union Road Map on Shared Responsibility and _______________ 26 10/26 See A/70/811, sect. III, table 1.